As countries work to achieve HIV epidemic control, the scale-up of high-quality differentiated service delivery (DSD) is a promising approach to improving both the quality and efficiency of HIV services. In response, ICAP at Columbia University launched the HIV Coverage, Quality, and Impact Network (CQUIN) in March 2017, with the support of the Bill & Melinda Gates Foundation. CQUIN is a learning network designed to accelerate DSD scale-up by fostering joint learning, south-to-south exchange, and targeted technical assistance for its member countries.